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• Mean activities

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• Activity deltas table
• Regulatory interactions
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Motif ID: MEF2{A,B,C,D}.p2

Z-value: 1.074

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_-_11838260	1.645	NM_015204	THSD7A	thrombospondin, type I, domain containing 7A
chr9_-_21218132	1.431	NM_021268	IFNA17	interferon, alpha 17
chr10_+_118340460	1.143	NM_006229	PNLIPRP1	pancreatic lipase-related protein 1
chr20_+_11846536	1.072	NM_014962	BTBD3	BTB (POZ) domain containing 3
chr3_+_50291521	1.010	NM_153215	C3orf45	chromosome 3 open reading frame 45
chr3_+_101316463	1.008	NM_001167924	C3orf26	chromosome 3 open reading frame 26
chr11_+_91724909	0.957	NM_001008781	FAT3	FAT tumor suppressor homolog 3 (Drosophila)
chr9_+_5221401	0.877	NM_002195	INSL4	insulin-like 4 (placenta)
chr6_-_123999640	0.847	NM_006073	TRDN	triadin
chr9_+_21430439	0.834	NM_024013	IFNA1	interferon, alpha 1
chr9_+_5440455	0.814	NM_014143	CD274	CD274 molecule
chr2_+_225973845	0.792	NM_020864	KIAA1486	KIAA1486
chr2_+_37282516	0.789		LOC100505876	hypothetical LOC100505876
chr4_-_80548378	0.731	NM_033214	GK2	glycerol kinase 2
chr13_-_49597776	0.722		DLEU2	deleted in lymphocytic leukemia 2 (non-protein coding)
chr17_+_71235324	0.707		ITGB4	integrin, beta 4
chr13_+_110637173	0.688	NM_001113513	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr11_-_30910074	0.684	NM_020869	DCDC5	doublecortin domain containing 5
chr3_-_48573556	0.682		PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr9_-_21229975	0.666	NM_002172	IFNA14	interferon, alpha 14
chr21_-_35153664	0.648		RUNX1	runt-related transcription factor 1
chr19_+_4983899	0.634
chr7_+_28415495	0.625		LOC401317	hypothetical LOC401317
chr17_+_35075124	0.617	NM_003673	TCAP	titin-cap (telethonin)
chr20_+_9236446	0.615	NM_000933	PLCB4	phospholipase C, beta 4
chr2_-_210876560	0.609	NM_079422	MYL1	myosin, light chain 1, alkali; skeletal, fast
chr1_-_188713324	0.608	NM_199051	FAM5C	family with sequence similarity 5, member C
chr1_-_154727014	0.603		MEF2D	myocyte enhancer factor 2D
chr2_+_214984705	0.602	NM_001080500	VWC2L	von Willebrand factor C domain containing protein 2-like
chr3_-_193928038	0.599	NM_004113	FGF12	fibroblast growth factor 12
chr4_-_143987053	0.594	NM_001101669 NM_003866	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa
chr15_-_70288071	0.567		PKM2	pyruvate kinase, muscle
chr12_-_3472245	0.565		LOC100129223	hypothetical LOC100129223
chr15_+_63156206	0.558	NM_001101362	KBTBD13	kelch repeat and BTB (POZ) domain containing 13
chr2_-_20390601	0.557	NM_015317	PUM2	pumilio homolog 2 (Drosophila)
chr15_+_76345577	0.544	NM_001130183	DNAJA4	DnaJ (Hsp40) homolog, subfamily A, member 4
chr17_-_2913650	0.539	NM_014566	OR1D4 OR1D5	olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene) olfactory receptor, family 1, subfamily D, member 5
chr12_+_79625538	0.539	NM_002469	MYF6	myogenic factor 6 (herculin)
chrX_-_21686079	0.538	NM_014332	SMPX	small muscle protein, X-linked
chr10_-_121592020	0.538		MCMBP	minichromosome maintenance complex binding protein
chr4_-_122521562	0.536	NM_198179	QRFPR	pyroglutamylated RFamide peptide receptor
chr14_-_106193403	0.533		IGKV3-20	immunoglobulin kappa variable 3-20
chr2_-_165259334	0.529		COBLL1	COBL-like 1
chr21_-_35174742	0.525		RUNX1	runt-related transcription factor 1
chr12_-_44877769	0.522		SLC38A1	solute carrier family 38, member 1
chr14_-_30927931	0.517	NM_015473	HEATR5A	HEAT repeat containing 5A
chr11_+_68124400	0.512		PPP6R3	protein phosphatase 6, regulatory subunit 3
chr15_-_68781662	0.510	NM_001008224	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats
chr21_-_18697829	0.509	NM_002772	TMPRSS15	transmembrane protease, serine 15
chr2_-_55053398	0.505
chr9_-_21156609	0.503	NM_002175	IFNA21	interferon, alpha 21
chr16_+_65868913	0.482	NM_015432	PLEKHG4	pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr9_-_21375258	0.477	NM_000605	IFNA2	interferon, alpha 2
chr7_-_113346284	0.461	NM_002711	PPP1R3A	protein phosphatase 1, regulatory (inhibitor) subunit 3A
chr14_+_71065794	0.458	NM_015556	SIPA1L1	signal-induced proliferation-associated 1 like 1
chr11_-_47330797	0.457	NM_000256	MYBPC3	myosin binding protein C, cardiac
chr2_-_224574860	0.451		SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr11_+_69176391	0.451		CCND1	cyclin D1
chr12_-_21985433	0.450		ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr4_+_70896236	0.448	NM_001009181 NM_003154	STATH	statherin
chr10_+_50177192	0.448	NM_001135196 NM_199459	C10orf71	chromosome 10 open reading frame 71
chr12_+_56802	0.447	NM_015232	IQSEC3	IQ motif and Sec7 domain 3
chr11_+_64838882	0.442	NM_006779	CDC42EP2	CDC42 effector protein (Rho GTPase binding) 2
chr5_-_58688428	0.440	NM_001197219	PDE4D	phosphodiesterase 4D, cAMP-specific
chr2_+_20510312	0.437	NM_004040	RHOB	ras homolog gene family, member B
chr4_-_46690197	0.434	NM_000809	GABRA4	gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr3_+_35658852	0.430	NM_016300	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr8_+_67201684	0.429	NM_033058 NM_184085 NM_184086 NM_184087	TRIM55	tripartite motif containing 55
chr6_+_55300225	0.427	NM_207410	GFRAL	GDNF family receptor alpha like
chr11_-_88436463	0.427	NM_000842	GRM5	glutamate receptor, metabotropic 5
chr8_+_120148604	0.424	NM_006438	COLEC10	collectin sub-family member 10 (C-type lectin)
chr1_-_151784889	0.423	NM_002961 NM_019554	S100A4	S100 calcium binding protein A4
chr22_-_40941254	0.421	NM_005650 NM_181492	TCF20	transcription factor 20 (AR1)
chr1_-_214963279	0.421	NM_001438	ESRRG	estrogen-related receptor gamma
chr8_-_131483395	0.420	NM_018482	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr19_+_42409205	0.420	NM_152604	ZNF383	zinc finger protein 383
chr13_-_102209422	0.414	NM_001146197	C13orf40	chromosome 13 open reading frame 40
chr17_+_65677255	0.411	NM_000891	KCNJ2	potassium inwardly-rectifying channel, subfamily J, member 2
chr9_+_102987137	0.411	NM_017753	LPPR1	lipid phosphate phosphatase-related protein type 1
chr10_+_91082218	0.409	NM_001031683	IFIT3	interferon-induced protein with tetratricopeptide repeats 3
chr2_-_27469947	0.405		FTH1P3	ferritin, heavy polypeptide 1 pseudogene 3
chr13_-_97916768	0.404		STK24	serine/threonine kinase 24
chr22_+_30670592	0.404		YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr16_-_73830025	0.403		BCAR1	breast cancer anti-estrogen resistance 1
chr2_+_204509698	0.402	NM_012092	ICOS	inducible T-cell co-stimulator
chr17_-_9870292	0.400	NM_001130831	GAS7	growth arrest-specific 7
chr17_-_31231421	0.400	NM_002985	CCL5	chemokine (C-C motif) ligand 5
chr10_-_69125932	0.396	NM_013266	CTNNA3	catenin (cadherin-associated protein), alpha 3
chr14_-_62854315	0.387	NM_145171	GPHB5	glycoprotein hormone beta 5
chr7_-_56128098	0.384	NM_006213	PHKG1	phosphorylase kinase, gamma 1 (muscle)
chr17_+_5913149	0.382		WSCD1	WSC domain containing 1
chr14_-_57133361	0.379	NM_001080455	SLC35F4	solute carrier family 35, member F4
chr2_-_215956429	0.379		FN1	fibronectin 1
chr20_-_54013418	0.378	NM_080617	CBLN4	cerebellin 4 precursor
chr2_+_170074457	0.378	NM_006063	KBTBD10	kelch repeat and BTB (POZ) domain containing 10
chr18_-_46046771	0.378	NM_145020	CCDC11	coiled-coil domain containing 11
chr9_-_129679760	0.377	NM_000476	AK1	adenylate kinase 1
chr1_+_144124547	0.376	NM_145277 NM_202004 NM_213652 NM_213653	HFE2	hemochromatosis type 2 (juvenile)
chr22_+_30670543	0.374		YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr3_+_122794859	0.371	NM_016298	FBXO40	F-box protein 40
chr11_+_35154775	0.371		CD44	CD44 molecule (Indian blood group)
chr12_-_110410730	0.365		ATXN2	ataxin 2
chr8_+_104900591	0.363	NM_014677	RIMS2	regulating synaptic membrane exocytosis 2
chr15_-_76378957	0.361	NM_025234	WDR61	WD repeat domain 61
chr1_-_156816312	0.361	NM_001004477	OR10X1	olfactory receptor, family 10, subfamily X, member 1
chr12_-_44919818	0.361		SLC38A1	solute carrier family 38, member 1
chr15_+_92700167	0.360	NM_001159644	MCTP2	multiple C2 domains, transmembrane 2
chr12_+_21175394	0.360	NM_006446	SLCO1B1	solute carrier organic anion transporter family, member 1B1
chr7_+_18501876	0.359	NM_014707 NM_178423	HDAC9	histone deacetylase 9
chr17_-_70367479	0.358	NM_000835	GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr1_-_85816520	0.358	NM_001134445	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr7_-_83108682	0.358	NM_001178129	SEMA3E	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr22_+_30670435	0.357	NM_003405	YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr10_+_96688399	0.353	NM_000771	CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9
chr2_-_36929520	0.351		STRN	striatin, calmodulin binding protein
chr5_-_94250357	0.351		MCTP1	multiple C2 domains, transmembrane 1
chr8_+_50147455	0.350	NM_001007176	C8orf22	chromosome 8 open reading frame 22
chr4_-_21308415	0.348	NM_001035003	KCNIP4	Kv channel interacting protein 4
chr3_-_101316038	0.347	NM_001042459 NM_182909	FILIP1L	filamin A interacting protein 1-like
chr9_-_33385265	0.347		AQP7	aquaporin 7
chr10_-_127559841	0.345	NM_018180	DHX32	DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr1_+_36394044	0.345		MAP7D1	MAP7 domain containing 1
chr2_-_200038055	0.344	NM_001172517	SATB2	SATB homeobox 2
chr11_-_84311867	0.344		DLG2	discs, large homolog 2 (Drosophila)
chr18_+_59405513	0.343	NM_012397	SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13
chrX_-_116991728	0.343	NM_033495 NM_001168300	KLHL13	kelch-like 13 (Drosophila)
chr1_+_36394338	0.343	NM_018067	MAP7D1	MAP7 domain containing 1
chr13_-_96444604	0.343	NM_080818	OXGR1	oxoglutarate (alpha-ketoglutarate) receptor 1
chr12_-_242255	0.340	NM_001190997 NM_016615	SLC6A13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13
chr14_-_103058865	0.339	NM_001823	CKB	creatine kinase, brain
chr22_-_36907638	0.338	NM_001004426 NM_003560	PLA2G6	phospholipase A2, group VI (cytosolic, calcium-independent)
chr21_-_33709037	0.338
chr9_+_80134302	0.336		PSAT1	phosphoserine aminotransferase 1
chr16_+_31132842	0.327	NM_001008274	TRIM72	tripartite motif containing 72
chr3_-_109730858	0.326	NM_014981	MYH15	myosin, heavy chain 15
chr4_+_37569093	0.321	NM_015173	TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr11_+_128751044	0.321	NM_003658	BARX2	BARX homeobox 2
chr3_+_99350859	0.319	NM_001005514	OR5H14	olfactory receptor, family 5, subfamily H, member 14
chr14_-_93493519	0.318	NM_016150	ASB2	ankyrin repeat and SOCS box containing 2
chr19_+_23091616	0.317		ZNF730	zinc finger protein 730
chr2_+_102744921	0.311	NM_144632	TMEM182	transmembrane protein 182
chr18_+_59705918	0.308	NM_001143818 NM_002575	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr13_-_50315832	0.308	NM_198989	DLEU7	deleted in lymphocytic leukemia, 7
chr11_+_35922106	0.307	NM_174902	LDLRAD3	low density lipoprotein receptor class A domain containing 3
chr5_-_150501393	0.307	NM_001193544	ANXA6	annexin A6
chr11_-_128399218	0.305	NM_014715	ARHGAP32	Rho GTPase activating protein 32
chr4_+_119174947	0.304	NM_004784	NDST3	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr6_+_33047952	0.301		BRD2	bromodomain containing 2
chr18_-_59480082	0.300	NM_006919	SERPINB3 SERPINB4	serpin peptidase inhibitor, clade B (ovalbumin), member 3 serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr10_+_95507555	0.299	NM_005097	LGI1	leucine-rich, glioma inactivated 1
chr3_+_137224266	0.299	NM_181897	PPP2R3A	protein phosphatase 2, regulatory subunit B'', alpha
chr8_-_102005697	0.297		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr22_+_40372957	0.296		XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6
chr9_+_74326536	0.296	NM_138691	TMC1	transmembrane channel-like 1
chr4_-_70547962	0.296	NM_006798	UGT2A1	UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr3_+_99370233	0.296	NM_001005515	OR5H15	olfactory receptor, family 5, subfamily H, member 15
chr19_+_57540493	0.295	NM_173530	ZNF610	zinc finger protein 610
chr9_-_21067804	0.295	NM_002176	IFNB1	interferon, beta 1, fibroblast
chr14_-_103058568	0.293		CKB	creatine kinase, brain
chr13_-_97972252	0.293	NM_003576	STK24	serine/threonine kinase 24
chr11_-_19180092	0.293	NM_001127656 NM_003476	CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr1_-_26266571	0.292	NM_032588	TRIM63	tripartite motif containing 63
chr6_+_127940011	0.292	NM_001010905	C6orf58	chromosome 6 open reading frame 58
chr14_-_94669547	0.290	NM_001195573	DICER1	dicer 1, ribonuclease type III
chr17_-_59451662	0.290	NM_001099786 NM_001099787 NM_001099788 NM_001099789	ICAM2	intercellular adhesion molecule 2
chr3_+_99334230	0.288	NM_001005338	OR5H1	olfactory receptor, family 5, subfamily H, member 1
chr18_-_65766068	0.288		CD226	CD226 molecule
chr17_+_29606408	0.287	NM_002982	CCL2	chemokine (C-C motif) ligand 2
chr9_+_78246401	0.287	NM_001097634	GCNT1	glucosaminyl (N-acetyl) transferase 1, core 2
chr2_-_219742950	0.284	NM_001144889 NM_001144890 NM_144712	SLC23A3	solute carrier family 23 (nucleobase transporters), member 3
chr18_-_49944986	0.284		MBD2	methyl-CpG binding domain protein 2
chr2_+_169351294	0.283	NM_001171631	NOSTRIN	nitric oxide synthase trafficker
chr10_+_124660206	0.283	NM_001029888	FAM24A	family with sequence similarity 24, member A
chr10_-_81698840	0.281	NM_003019	SFTPD	surfactant protein D
chr2_-_228206045	0.279	NM_001162483 NM_020161	C2orf83	chromosome 2 open reading frame 83
chr14_-_20969706	0.278	NM_001170629	CHD8	chromodomain helicase DNA binding protein 8
chr3_+_190990142	0.278	NM_001114980 NM_001114981 NM_001114982	TP63	tumor protein p63
chr7_+_113853790	0.278	NM_001172767 NM_148899	FOXP2	forkhead box P2
chr17_-_15914485	0.277		NCOR1	nuclear receptor corepressor 1
chr2_+_113119985	0.275	NM_005415	SLC20A1	solute carrier family 20 (phosphate transporter), member 1
chr19_-_20540380	0.272	NM_001159293	ZNF737	zinc finger protein 737
chr3_-_47909001	0.270		MAP4	microtubule-associated protein 4
chr15_-_23204887	0.270	NM_000462	UBE3A	ubiquitin protein ligase E3A
chr9_-_129381086	0.269	NM_001035534	FAM129B	family with sequence similarity 129, member B
chr1_+_39569396	0.267	NM_033044	MACF1	microtubule-actin crosslinking factor 1
chr14_-_64479198	0.267	NM_002083	GPX2	glutathione peroxidase 2 (gastrointestinal)
chr10_-_126706442	0.266	NM_022802	CTBP2	C-terminal binding protein 2
chr12_-_47679459	0.266		DDN	dendrin
chr9_-_74169649	0.264	NM_001102420 NM_001102421 NM_006007	ZFAND5	zinc finger, AN1-type domain 5
chr2_+_219991342	0.262	NM_001927	DES	desmin
chr17_-_38087366	0.261	NM_016602	CCR10	chemokine (C-C motif) receptor 10
chr12_-_68291208	0.261	NM_201550	LRRC10	leucine rich repeat containing 10
chr12_-_48285526	0.260	NM_032130	FAM186B	family with sequence similarity 186, member B
chr14_+_95915774	0.258	NM_016472	C14orf129	chromosome 14 open reading frame 129
chr16_-_73830480	0.257	NM_001170721	BCAR1	breast cancer anti-estrogen resistance 1
chr17_-_46140015	0.257	NM_052855	ANKRD40	ankyrin repeat domain 40
chr5_+_67620007	0.257	NM_181524	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chrX_-_30237403	0.254	NM_000475	NR0B1	nuclear receptor subfamily 0, group B, member 1
chr7_+_80069439	0.252	NM_001001547	CD36	CD36 molecule (thrombospondin receptor)
chr13_-_35327798	0.252	NM_001195415 NM_001195416 NM_001195430	DCLK1	doublecortin-like kinase 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.18	2.96e-02	GO:0032501	multicellular organismal process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
3.13	9.14e-06	GO:0030016	myofibril
3.05	9.69e-06	GO:0043292	contractile fiber
2.99	7.55e-05	GO:0044449	contractile fiber part
3.06	2.20e-04	GO:0030017	sarcomere
1.35	7.48e-04	GO:0005576	extracellular region
1.47	5.56e-03	GO:0044421	extracellular region part
3.39	2.82e-02	GO:0031674	I band
1.48	4.74e-02	GO:0005615	extracellular space

Nothing significant found in function category.